Here at the Center for Carolina Living, we unfold the character of both North Carolina and South Carolina so you can explore regions and towns matching your aspirations. If you're planning on visiting the Carolinas, www.carolinaliving.com offers many great hotels deals. United States > South Carolina > Orangeburg > Comfort Inns Arrival Date Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Departure Date Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Adults 1 2 3 4 Children 0 1 2 3 4 Comfort Inns - Orangeburg South Carolina Comfort Inn & Suites 3671 Saint Matthews Rd. Orangeburg, SC 29115 Nightly Rates (67.49 - 105.95)   2 Star Easy on & off interstate access. The Comfort Inn & Suites is conveniently located less than one mile from the Orangeburg Regional Medical Center. This Orangeburg hotel is close to popular area attractions, including South Carolina State University, S Nearby Cities: Orangeburg ,  Saint George ,  Santee Orangeburg Hotel Chains Comfort Inns Days Inn Fairfield Inn by Marriott Holiday Inn Howard Johnson Plazas, Hotels, Inns, and Express Inns Quality Inns Sleep Inns Super 8 Motels